Artículos de Interés

For in vitro diagnostic use. PD-L1 IHC 22C3 pharmDx is a qualitative immunohistochemical assay using monoclonal mouse anti-PD-L1, Clone 22C3 intended for use in the detection of PD-L1 protein in formalin-fixed, paraffin-embedded (FFPE) non-small cell lung cancer (NSCLC)…

An aim of this study was to assess lung autopsy findings in COVID-19 inpatients, and in untreated severe acute respiratory syndrome coron- avirus 2 (SARS-CoV-2)-positive individuals who died in the community

Molecular and immunologic breakthroughs are transforming the management of thoracic cancer, although advances have not been as marked for malignant pleural mesothelioma where pathologic diagnosis has been essentially limited to three histologic subtypes.

Human epidermal growth factor receptor 2 protein (HER2/ neu or  HER2), encoded by the ERBB2 gene located on the long arm of chromosome 17, is a transmembrane tyrosine kinase protein. HER2 amplification and/or overexpression occurs in up to 20% of invasive breast cancers is linked with aggressive disease and poor prognosis…

Cutaneous malignant melanoma (CMM) is one of the most common skin cancers worldwide. Limited information in available in the current scientific literature on the concordance of genetic alterations between primary and metastatic CMM.

High grade serous carcinoma is the most common and devastating type of ovarian cancer; its etiology, mechanism of malignant transformation, and origin remain controversial. Recent studies have identified secretory cells at the fimbria of the fallopian tube  as the cell-of-origin of high-grade serous carcinoma, acquiring TP53 mutation…

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